
South America Tours & Vacations
Steeped in ancient traditions and adventurous landscapes, South America offers charismatic cities and breathtaking natural wonders. From the Amazon rainforest to Patagonian glaciers, white-sand beaches to Andean plains, the wonders of wildlife unlike anywhere else in the world abound. Whether interested in cultural treasures or timeless landscapes, South America is exceptionally diverse and endlessly enchanting. Zicasso travel specialists have planned over 40,000 trips to this region of the world and look forward to designing yours.
Top South America Destinations
Discover extraordinary places and those rarely explored–these are a few to inspire your travels.
Explore Our Trip Ideas
Let these itineraries inspire your personalized travel experience

8 Day Trip IdeaFrom $4,300
Paradisiacal Peru: Lima, Cusco, Sacred Valley Tour

9 Day Trip IdeaFrom $5,200
Colombia Cultural Immersion: 9-Day Tour of Bogota, Medellin, and Cartagena

10 Day Trip IdeaFrom $9,800
10-Day Brazil: Wildlife and Nature Explorer

12 Day Trip IdeaFrom $14,500
Argentina Explorer: Capital, Forests, Andes Mountains, and Wine Country

14 Day Trip IdeaFrom $11,600
Heart of Patagonia: Two-Week Tour of Chile and Argentina

14 Day Trip IdeaFrom $17,100
14 Day Galapagos Adventure
How Zicasso Works
Here's how we create life-enriching, luxury travel experiences
1.Share Your Travel Dreams
Zicasso specializes in custom tours, vacations, and safaris tailored to your interests and preferences. From private African safaris to culinary experiences in Europe, submit a trip request to share your ideas and travel style.
2.Meet Your Travel Specialists
To ensure a personalized experience, we'll carefully handpick and introduce you to two of our top travel specialists, each with unsurpassed destination knowledge and local insight aligned to your luxury travel dreams.
3.Design Your Perfect Journey
Compare the expertise of two specialists with itineraries crafted exclusively for you. You can refine these further and choose your preferred proposal. Our unique process ensures a more creative, personalized, and expertly crafted trip.

12 Day Trip IdeaFrom $12,700
Cultural Kaleidoscope Road Trip from Salta to the Atacama

13 Day Trip IdeaFrom $6,900
Highlights of Chile and Easter Island Tour: Expansive Desert to Remote Island

21 Day Trip IdeaFrom $23,600
Riveting Luxuries of Chile and Argentina Tour: Surreal Landscapes to Buzzing Cities

9 Day Trip IdeaFrom $3,700
Wonders of Chile: City, Desert, Mountain Tour

15 Day Trip IdeaFrom $8,000
Marvels of Peru and Brazil Tour: Natural and Cultural Discoveries

12 Day Trip IdeaFrom $6,800
Coffee, Chocolate & Cocktails Tour of Costa Rica
Popular Destinations in South America
Travel Tips for Your South America Trip
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Reviews of Zicasso's South America Tours & Vacations
Based on 2208 verified traveler reviews.
We received attention to detail, professional and knowledgeable guides, and great communication before and during the trip from Zicasso's tour operator.
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Our trip in Brazil was amazing! Zicasso’s trip expert organized our travel plans according to our wishes and went out of his way to compensate for any hiccups with other vendors. For example, he made sure we had an interpreter when we could not check in online for local flights.
It was really the most relaxing vacation ever because we did not have to worry about anything. Everything booked by the travel company was top-notch, our trip expert and local travel agents were available when needed, and the vendors he worked with were great! We highly recommend the travel company.
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This was a big and complex trip, but it went very smoothly and we were delighted with each segment of our travels.
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My husband and I had a fantastic time on our trip to Peru. I would highly recommend Zicasso’s travel agency! Our agent listened to all of our wants and needs, and certainly delivered! She even made a point to meet us in person and give us an anniversary gift, which was so thoughtful and unexpected.
A couple of things:
It would be great if the travel agency had an app that showed your daily itinerary. Other agencies have this and it makes it very convenient to understand where you are going and at what time.
Second, travelers, beware of the altitude! It really affected me, to the point where I needed oxygen. (By the way, the hotels make this readily available to guests.) I would ensure anyone going to Cusco/Machu Picchu is well aware of this. Also, we did not visit the Rainbow Mountain and I am glad we didn't. The altitude there is 5,000 meters, which is over 16,000 feet, which my body would not have been able to handle.
Overall, this was a trip of a lifetime and I want to thank the travel agent again for planning such a wonderful trip!
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We loved working with Zicasso’s tour operator for our trip to Peru. Our agent was incredibly responsive and organized. She listened to our ideas and preferences, and immediately got to work planning a trip that was perfect for us. She answered messages immediately and was flexible, but also gave honest and helpful feedback and suggestions. We would recommend this tour operator wholeheartedly to anyone planning a trip to Peru!
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The trip was amazing, with such attention to detail. The Zicasso travel company communicated frequently before and during the trip. Any changes were communicated and followed up on. The experiences offered were unique and personalized, and made the trip memorable!
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